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Resources

There is a lot to know about organ transplantation so don’t be overwhelmed.  We have compiled some medical resources as well as organizational and structural links that may be useful in your research. 

Organ Transplant System and Organizations

Organ Procurement Organizations (OPOs)

OPOs are responsible for coordinating the identification, evaluation, and recovery of organs from donors. They are nonprofit organizations designated by the federal government to serve specific regions. OPOs also handle the transportation of organs to transplant centers. OPOs are essential in ensuring the timely and ethical recovery and distribution of organs across the country. They work closely with donor hospitals and the national system to match organs with patients in need.

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United Network for Organ Sharing (UNOS)  

Unos manages the national transplant waiting list through the Organ Procurement and Transplantation Network (OPTN). It oversees the organ matching process based on factors such as blood type, medical urgency, organ size, and geographical location, using a computer algorithm. UNOS ensures that the organ allocation process is fair, transparent, and based on medical criteria, not financial or social status.Transplant Centershttps://srtr.org/transplant-centers These are the hospitals that perform the organ transplants. They evaluate patients, add eligible patients to the transplant list, perform the surgery, and provide post-transplant care. Transplant centers are vital in the execution of organ transplants and providing critical pre- and post-operative care to patients.

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The U.S. Department of Health and Human Services (HHS)  

The HHS oversees the organ transplantation system at the federal level, ensuring compliance with national laws and regulations. It also funds and manages various programs related to organ transplantation, including oversight of the OPTN through the Health Resources and Services Administration (HRSA). HHS ensures the system functions efficiently, ethically, and in accordance with federal laws.Organ Donation Advocacy and Educational OrganizationsNonprofit organizations such as Donate Life America focus on educating the public, promoting organ donation, and encouraging people to register as donors.Public awareness and donor registration are crucial for increasing the pool of available organs and addressing the organ shortage in the 

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U.S.Key Laws and Regulations:

National Organ Transplant Act (NOTA) of 1984

Established the framework for organ donation and transplantation in the U.S., prohibiting the sale of organs and creating the OPTN.

Uniform Anatomical Gift Act (UAGA)

Provides a legal framework for organ donation across states, ensuring consistency and promoting donor registration.

In the United States, organ transplantation involves a complex, regulated system to ensure that organs are allocated equitably and safely. Several entities play key roles in this system, each with specific functions to ensure the integrity of the process. Below is an explanation of these entities in order of their involvement, along with their importance and functions

 

:Donors and Donor Hospitals

This is where the organ donation process begins. Organ donors may be living or deceased, but the vast majority of organ donations come from deceased individuals who are brain-dead or in some cases have experienced cardiac death. Donor hospitals identify potential donors, maintain the organs in a viable state, and notify the appropriate authorities. The process starts with identifying and maintaining viable organs, which is critical to successful transplantation.

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